We appreciate big discoveries and we appreciate trivial ones too
We recently noticed that the widely used eGFP sequence may produce an unintended protein using certain construct designs. While the discovery itself is trivial, it sounded an alarm for more important biomedical constructs, such as those used in gene therapies, and this study will be a primer for a bigger effort where we employ the…
New manuscript on bioRxiv
Our manuscript titled “A long-read human pangenome initiative for comprehensive interpretation of nuclear-embedded mitochondrial DNA” has been put on bioRxiv. Cheers! Here is a podcast created based on this manuscript. Now you can listen to it while jogging or doing something else. Here is a video overview and OMG it is cute. Here is a…
Yujiao and Shushu will give oral presentations at MDA 2026
Highlighting the two projects I contributed to as a Yale Research Affiliate Sponsored Identity. Students and trainees can register for virtual attendance for free! A High-Throughput Assay for Measuring Ribitol Response Across FKRP Variants The assay employed in this project was dear to my heart. I was literally working remotely on analyzing the proof-of-concept experiments…
New manuscript on bioRxiv
Our manuscript titled “Joint Segmental Duplication Co-option Drives Human-specific Transcriptional Readthrough and Expression Fine-tuning of NPEPPS-TBC1D3” has been put on bioRxiv. Cheers!
The Horses' Taming Lab 